Nearly all children who admitted to a hospital intensive care unit (ICU) receive off-label medication. "Off label" is a term used to describe drugs that aren't approved by the U.S. Food and Drug Administration (FDA) for treatment of a particular condition. While it's legal for doctors to administer off-label uses of drugs, it comes with heightened risk since the FDA hasn't declared the medication safe for the particular purpose.
The osteoporosis drug Fosamax has already been linked to rare bone fractures and necrosis of the jawbone, but a new study reveals a more devastating side effect. Researchers at Northwestern University found that patients taking Fosamax have an increased risk of developing esophageal cancer.