In 2003, a girl's parents gave her ibuprofen to help battle a fever. The medication, manufactured by Motrin, caused a life-threatening side effect known as toxic epidermal necrosis (TEN). The reaction caused the 7-year-old to suffer brain damage and irreparable damage to her respiratory system. Unfortunately, that wasn't all that happened: TEN caused her to lose more than 90 percent of her skin and go blind.
The anti-smoking drug Chantix continues to be scrutinized by the U.S. Food and Drug Administration (FDA) and consumer watchdogs. The concerns about Pfizer's smoking cessation drug began when consumers began to report that it caused them to suffer depression and suicidal behavior.